ROSSIX AB i Mölndal 556830-3183 - Merinfo.se

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Rossix - UTVECKLINGSBYRÅER, Mölndal - Rossix i Molndal - TEL

PLL1851 X & Swirl gently before use Composition 201612 2-8 •c, Do not freeze Phospholipid emulsion containing a mixture of highly purified phosphatidyl choline (PC), phosphatidyl serine (PS) and sphlngomyelln (SM). Quality Manager, Rossix AB T-RX044, Rev 1 Rossix AB Taljegardsgatan 38 SE-431 53 Molndal Sweden Phone: +46 31 706 8965 Fax: +46 31 706 8966 info@rossix.com www .rossix.com 1 (1) January 11, 2017 Date Rossi.x Rox Phospholipid (PL052) is for determination of single pro- and anticoagulant proteins, Phospholipid is suitable for use in chromogenic methods comprising phospholipids for determination of e.g. FII, FV, FVIII, FIX, FX, Protein C and Protein S. Manufactured by Rossix AB. The intended use of Rossix phospholipid emulsions is as a procoagulant phospholipid source in global and specifi c hemostasis methods used in R&D and Quality Control. Both phospholipid emulsions contain highly purifi ed or synthetic sources of phosphatidylserine, phosphatidylcholine and sphingomyelin. A characteristic feature of Rossix phospholipid mixture was purchased from DiaPharma.

Rossix phospholipid

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A stabilized phospholipid emulsion, with defined content, was a kind gift from Dr. Steffen Rosén, Rossix. The emulsion, denoted TGT, contained 0.5 mmol/L phospholipids based on a mixture of 28 mol% phosphatidylserine, 30 mol% sphingomyelin. and 42 mol% phosphatidylcholine. In brief, subsamples or human FXa calibrators (Enzyme Research Laboratories) were incubated at 37°C for 3 minutes, followed by addition of human FII, bovine FVa, phospholipid-TGT (all from Rossix), and CaCl 2. During a 3-minute activation at 37°C, prothrombinase (FXa+FVa) catalyzed the conversion of FII (prothrombin) into FIIa (thrombin Human NPP or FXI‐DP (50% f.v, Affinity Biologicals) was mixed with a fluorogenic substrate for thrombin Z‐GGR‐AMC (800 µM f.c., Bachem), phospholipid vesicles (12 µM f.c., Rossix AB), and recombinant tissue factor (TF, 0.1 pM f.c., ~1:60,000 dilution of RecombiPlasTin; Instrumentation Laboratory, Bedford, MA, USA). Over 60% differences in estimates by OSCA were observed, with no correlation with activators or phospholipid within the reagents. Rossix CHA gave 40% lower results than the Hyphen CHA kit.

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Activation of coagulation in plasma samples is initiated by addition of an activation mix, containing tissue factor (Innovin, Siemens, Marburg, Germany, with final concentration 2 pM), phospholipids (Rossix, Mölndal, Sweden, final 4 µM), and calcium chloride (final 20 nM) inside of transparent 96-well microtiter plates (nunc, Thermofisher Scientific, Bremen, Germany), and the increase in OD Reagent B contains lyophilized bovine FXIa, calcium chloride and phospholipids. Reconstitute with 8.0 mL water. Allow to stand for 5 min at 20-25oC with intermittent gentle mixing for complete reconstitution.

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Rossix phospholipid

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Rossix phospholipid

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The indicated concentrations are final concentration in the reaction mixture.

The intended use of Rossix phospholipid emulsions is as a procoagulant phospholipid source in global and specifi c hemostasis methods used in R&D and Quality Control. Both phospholipid emulsions contain highly purifi ed or synthetic sources of phosphatidylserine, phosphatidylcholine and sphingomyelin. A characteristic feature of This phospholipid emulsion is suitable for use in the NAPTT method and in hemostasis research related to procoagulant and anticoagulant pathways. Package 10 x 3 mL Over 60% differences in estimates by OSCA were observed, with no correlation with activators or phospholipid within the reagents.
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and 42 mol% phosphatidylcholine. Over 60% differences in estimates by OSCA were observed, with no correlation with activators or phospholipid within the reagents. Rossix CHA gave 40% lower results than the Hyphen CHA kit. There was substantial OSCA and CHA disparity with an average OSCA/CHA ratio of 2.2.


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The polyclonal goat anti–mouse-PRCP antibody (anti-TND20) was reared with a peptide from the mouse PRCP amino acid sequence TNDFRKSGPYCSESIRKSWN at Q.C.B. Custom Antibody Service. Human coagulation factors XIIa, Human NPP or FXI‐DP (50% f.v, Affinity Biologicals) was mixed with a fluorogenic substrate for thrombin Z‐GGR‐AMC (800 µM f.c., Bachem), phospholipid vesicles (12 µM f.c., Rossix AB), and recombinant tissue factor (TF, 0.1 pM f.c., ~1:60,000 dilution of RecombiPlasTin; Instrumentation Laboratory, … Heterogeneous effect of direct oral anticoagulants on lupus anticoagulant assays. ISTH Academy. Lindahl T. 07/07/19; 263351; PB0163 Topic: Laboratory Diagnostics - Thrombosis In this video, we look at phospholipids, comparing them to triglycerides, and looking at their properties.

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We are experts in chromogenic assays for coagulation factors and our experience goes back to the development of the first commercial chromogenic assay for Factor VIII in the 1980’s. Rossix develops and manufactures premium quality reagents for hemostasis research, diagnostics and quality control. We are experts in chromogenic assays for coagulation factors and our experience goes back to the development of the first commercial chromogenic assay for Factor VIII in the 1980’s. Rossix Phospholipid-TGT 3 ml 0.5 mM Phospholipid Emulsion For In Vitro Research Use Only !REF! PL604T !LOT! PLL1851 X & Swirl gently before use Composition 201612 2-8 •c, Do not freeze Phospholipid emulsion containing a mixture of highly purified phosphatidyl choline (PC), phosphatidyl serine (PS) and sphlngomyelln (SM).

Product range Our product range consists of chromogenic assays for coagulation factors, phospholipid emulsions and buffers. Rossix Phospholipid-TGT is a phospholipid emulsion is suitable for use in hemostasis research related to procoagulant and anticoagulant pathways such as in thrombin generation (TGT). The 0.5 mM emulsion is specially suitable for use in TGT assays in the presence of activated Protein C (APC). Phospholipid. A long term stable 0.25 mM Phospholipid emulsion with high procoagulant activity suitable for use in global NAPTT methods and for use in other methods comprising phospholipids for determination of pro- and anticoagulant proteins. Rossix Phospholipid Emulsion is a stabilized phospholipid emulsion with high procoagulant activity. This phospholipid emulsion is suitable for use in hemostasis research related to procoagulant and anticoagulant pathways.