Molecular Interactions - Biacore T100 — Helsingfors universitet
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The Biacore T100 is a state-of-the-art surface plasmon resonance instrument that combines high sensitivity with automated high throughput, making it an ideal instrument for the study of biomolecular i Biomolecular interactions can either be measured label-free with Biacore T100 using surface plasmon resonance (SPR) or with Monolith NT.115 using MicroScale Thermophoresis (MST). With SPR, one partner of the complex is immobilized onto the surface of a chip and with MST, the interactions are studied in solution while one partner is fluorescently labelled. Biacore T100 is a versatile, label-free system for detailed studies of biomolecular interactions. It is fully automated and enables fast screening of many interactions. The chips are equipped with four flow cells offering three ligands to be tested simultaneously (first flow cell serves as a reference cell for non-specific binding). Biacore（生体分子間相互作用解析） キーワード・製品名・コード番号からマニュアルを探す Biacore T200 (lower sensorgram) compared to Biacore T100 (upper sensorgram) when using low levels of immobilized GPCR. Data courtesy of Dr. Andrei Zhukov, Heptares Therapeutics Ltd, Welwyn Garden City, UK. Biacore T200 is designed for the analysis of molecular interactions where high sensitivity is crucial: Biacore T200 software v3.2 evaluation tools strengthen the applicability of Biacore T200 system for comparability and biosimilar studies.
The chips are equipped with four flow cells offering three ligands to be tested simultaneously (first flow cell serves as a reference cell for non-specific binding). Biacore（生体分子間相互作用解析） キーワード・製品名・コード番号からマニュアルを探す Biacore T200 (lower sensorgram) compared to Biacore T100 (upper sensorgram) when using low levels of immobilized GPCR. Data courtesy of Dr. Andrei Zhukov, Heptares Therapeutics Ltd, Welwyn Garden City, UK. Biacore T200 is designed for the analysis of molecular interactions where high sensitivity is crucial: Biacore T200 software v3.2 evaluation tools strengthen the applicability of Biacore T200 system for comparability and biosimilar studies. The main new functionalities include additions to the sensorgram comparison module.
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Biacore T100 GxP Handbook describes functionality added with the optional GxP package, together with some recommendations for using the system in a regulated environment. Biacore t100 biacore T100 Biacore, supplied by Biacore, used in various techniques. Bioz Stars score: 88/100, based on 2 PubMed citations.
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· Streamlined workflow One-click (for Biacore T200, Biacore T100, Biacore.
Caps for 7 mm plastic vials, 40 pcs Ventilated kraton G (SEBS) rubber caps, diam. 7 mm.
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It characterizes molecules in terms of the specificity of interaction, on and off -rates (kinetics), binding strength (affinity) and thermodynamics. Biacore T100. Label-free interaction analysis in real time.
The antibody/antigen interactions were studied by SPR via a capture technique, with anti-human Fc as ligand and purified CA IX-ECD-C9 as analylyate using Biacore T100. Biacore T100 System Operation Kit . Control & Evaluation software for Biacore T100 system. (May also be installed on one additional PC.) BR-1006-45.
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• Save assay development time with single-cycle kinetics. • Generate high quality data kinetics data for interactions that previously Biacore T100 Manual Biacore Assay Hbk3.book Page 7 Friday, May 4, 2012 3:12 PM. 1 Introduction 1.5 Biacore terminology 8 Biacore Assay Handbook 29-0194- Surface plasmon resonance measurements were performed using a BIAcore RU (RMS) for the T200, T100 and 3000 systems respectively; sourced directly Device: Biacore T100. Description: High performance system for analysis of biomolecular interactions, based on surface plasmon resonance (SPR) technology. Biacore T200 is a versatile and precise surface plasmon resonance (SPR) system that provides you with a wide range of high-quality molecular interaction data.
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Biacore T100 Software products and additional licenses.
The fully automated operation and independent temperature control for the detection chamber and sample chamber allows streamline and unattended operation for up to 4 days. Biacore T100 Software Handbook BR-1006-48 Edition AE Page 12 1 Introduction 1.4 Biacore terminology Figure 1-2. Schematic illustration of a sensorgram. The bars below the sensorgram curve indicate the solutions that pass over the sensor surface.